Magnesium is best taken at night before sleep as it relaxes the muscles. It contains zinc that’s been attached to a chelating agent. 10 mg/d of zinc on an empty stomach is sufficient to prevent or reverse a deficiency, but this should be doubled in an acute crisis of diarrhea or with chronic intestinal malabsorption. If most of your meals are rich in fruits and vegetables (like they should be!) Zinc deficiency in the elderly may be related to ulcers, dermatitis, hair … I always see labels suggesting use of ZMA on an empty stomach. High doses above the recommended amounts might cause fever, coughing, stomach pain, fatigue, and many other problems. Taking more than 100 mg of supplemental zinc daily or taking supplemental zinc for 10 or more years doubles the risk of developing prostate cancer. Deficiencies and Excesses Since fruits and grains are not optimal sources of zinc, vegans and vegetarians can be deficient in zinc as vegetables. Skip the stomach ache by taking them with food, using easy-to-digest formats and reducing your dose size. In any case, I would suppose a good purpose to supplement w/zinc at bedtime would be if you're also taking B-6 and magnesium aka ZMA. What she told me next blew me away. Zinc is involved in over 300 known proteins in the body, yet as we age, zinc status tends to decline. Taking vitamins on an empty stomach can make you feel sick. Zinc and magnesium are best absorbed on an empty stomach, but if it messes with your stomach have it with some food. Chelating agents are chemical compounds that bond with metal ions (such as zinc… Email. She started drinking a half teaspoon then worked up to a tablespoon of diatomaceous earth every night. Some people experience nausea when taking NAC on an empty stomach, but the majority of people do not experience any side effects if they take it with food. She took it 2 hours after her last meal, apparently you have to take this stuff on an empty stomach. Chelated zinc is a type of zinc supplement. Iron, magnesium and fish oil supplements are the most common culprits for digestive upset when taken on an empty stomach, so take extra care to have these with a meal or snack. Take zinc in the morning just before breakfast and then take magnesium at night before sleeping to help with muscle soreness and recovery. ReddIt. While the general requirement is 10-15mg/day of zinc for adults, the elderly may need much more. She was able to not only stop taking synthroid, but her addiction to the drug disappeared. Zinc should be taken on an empty stomach last thing at night. I just make sure I haven't eaten anything in about an 1-1.5 hrs (max) when I take a supplement that is suggested to be taken on an empty stomach. 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